Dental caries in children and adolescents with type 1 Diabetes

systematic review and meta-analysis

Authors

  • Isabela Queiroz Magnani Universidade Federal de Minas Gerais
  • Yasmin Pissolati Mattos Bretz Universidade Estadual de Campinas
  • Gabriela Luíza Nunes Souza Universidade Federal de Minas Gerais
  • Lucas Guimarães Abreu Universidade Federal de Minas Gerais https://orcid.org/0000-0003-2258-8071

DOI:

https://doi.org/10.35699/2178-1990.2021.27061

Keywords:

Dental caries, Diabetes mellitus, Child, Adolescent, Review, Meta-analysis as topic

Abstract

Aim: The aim of this systematic review and meta-analysis was to evaluate studies in which children/adolescents with type 1 Diabetes (DM1) were compared with children/adolescents without DM1 as regards dental caries.

Methods: Electronic searches in Web of Science, Scopus, Lilacs, PubMed, OpenGrey, and Google Scholar databases were conducted up to December/2020. Study selection was carried out separately by two reviewers. References that met the eligibility criteria were included. Risk of bias was evaluated using the Newcastle Ottawa scale. Meta-analyses were conducted. Mean difference (MD) and confidence intervals (CI) were provided.

Results: In the database searches, 751 references were retrieved. Following the removal of 102 duplicates, 649 references were assessed, and 16 studies were included in this systematic review and meta-analysis. Discrepancies in results were found among the included studies. Two meta-analyses demonstrated no significant difference between children/adolescents with DM1 and children/adolescents without DM1 regarding the mean number of permanent teeth with caries (MD = 0.07; CI = -0.68 – 0.82), as well as no significant difference between children/adolescents with DM1 and children/adolescents without DM1 with respect to the mean number of permanent tooth surfaces with caries (MD = 0.20; CI = -2.22 – 2.61). The third meta-analysis revealed that children/adolescents without DM1 had a significantly higher mean number of primary teeth with caries in comparison to children/adolescents with DM1 (MD = 0.34; CI = 0.31 – 0.37). The major issues in the risk of bias assessment were the definition of controls and comparison between cases and controls.

Conclusion: The occurrence of caries seems to be lower in children/adolescents with DM1 than in children/adolescents without DM1.

 

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Published

2022-03-15

How to Cite

Magnani, I. Q., Bretz, Y. P. M. ., Souza, G. L. N. ., & Abreu, L. G. (2022). Dental caries in children and adolescents with type 1 Diabetes: systematic review and meta-analysis. Arquivos Em Odontologia, 57, 175–188. https://doi.org/10.35699/2178-1990.2021.27061

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