Clinical evaluation to the frequency of oral complications and its relation with the quality of buccal hygiene in pediatric patients submitted to antineoplastic treatment
Keywords:
Medical oncology, Drug therapy, Adverse effects, Radiotherapy, Mouth, Drug effects, ChildrenAbstract
This study it has as objective to evaluate and to identify the presence of decurrent acute oral complications of the antineoplastic treatment beyond on condition that correlating buccal health in 59 pediatrics patients submitted the antineoplastic treatment in the CEONH/HUOC, with age between 0 and 18 years. The clinical aspect of the buccal mucosa was evaluated in weekly intervals, the stream bed, under artificial light, with the aid of language step-Down, of the beginning to the ending of the oncologic treatment. For the clinical evaluation of the mucositis the criterion of acute toxicity of World Health Organization was used (WHO). The buccal health was evaluated in the first consultation, through the visual inspection and was classified as favorable or favorable. Of the 59 patients, 36 (61%) preseated favorable buccal health. Of the oral complications that involved the patients with buccal quality of favorable hygiene, candidiasis corresponded 45.2%, in the patients that they had presented quality of favorable buccal hygiene, candidiasis corresponded 26.1% of the verbal complications. The mucositis also was more frequent in the patients with quality of favorable buccal hygiene, 28.6% of the oral complications. The orientation to the patients and its responsible on the necessity and importance of rigorous a buccal hygiene are indispensable, considering that the buccal health is one of the factors that favor the appearance and increase of the severity of the decurrent acute oral complications of the antineoplastic treatment.
Downloads
References
Rosa LN. Atenção estomatológica aos pacientes pediátricos oncológicos submetidos a tratamento quimioterápico e à radioterapia. RGO 1997 mar./abr.; 45: 111-114.
Ferreti AG, Raybold TP, Brown AT et al. Chlorhexidine prophylaxis for chemotherapy and radiotherapy-induce stomatitis: a randomized double-blind trial. Oral Surg Oral Med oral Pathol 1990; 69: 331-338.
Nikoui M, Lalonde B. Oro-dental manifestations of leukemia in children. J Can dent Assoc, Montreal, 1996; 5: 443-450.
Marques APF, Walker PO. Intra oral etiology of a life-threatening infection in na immunocompromised: report of case. J Dent Child 1991; 492-495. 5. Childers EA, Stinnett P, Wheeler P et al. Oral complications in children with cancer. Oral Surg Oral Med Oral Pathol 1993;75: 41-47.
Fayle SUA, Duggal MS, Williams SA. Oral problems and the dentists role in the management of pediatric oncology patients. Dent Update 1992;19: 152-159.
Gordón-Núñez MA, Pinto LP. Candidíase e sua relação com a mucosite oral em pacientes oncológicos pediátricos. RBPO 2003; 2:22-24.
Sonis ST. Oral complications of câncer therapy. In: De Vita Jr VT, Hellmann S, Rosenberg SA. Cancer Principles and Practice of Oncology, Philadelphia: J.B. Lippincott Company, 1993;24: 2385-2393.
Sonis ST et al. Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 2001; 19: 2201-2205.
Borowski B, Benhamou E. Pico JL. et al. Prevention of oral mucositis in patients treated with high-dose chemotherapy and bone marrow transplantation: a randomised controlled trial comparing two protocols of dental care. Eur J Cancer B Oral Oncol 1994;30B: 93-97.
McGuire DB, Altomonte V, Peterson DE et al. Patterns of mucositis and pain in patients receiving preparative chemotherapy and bone marrow transplantation. Oncol Nurs Forum, Atlanta, 1993; 20: 1493-1502.
Woo SB, Sonis ST, Monopoli MM et al. A longitudinal study of oral ulcerative mucositis in bone marrow transplant recipients. Cancer 1993; 72: 1612-1617.
Epstein JB, Schubert MM. Oral mucositis in myelosuppressive cancer therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, St Louis, 1999; 88: 273-276.
Gobetti JP. Prevention and Management of Oral complications of chemotherapy. Dent Assis 1993; 62: 31-33.
Loprinzi CL, Gastineau DA, Foote RL. Oral Complications. In: Abeloff MD, Armitage JO. Lichker AS et al. Clinical Oncology. New York : Churchill Livingstone, 1995: 741-749.
Almeida PNM. Avaliação clínico-epidemiológica da mucosite oral radioinduzida. Trabalho de Conclusão de Curso Faculdade de Odontologia de Pernambuco, 2004.
Parise Jr O. Câncer de boca: aspectos básicos e terapêuticos. São Paulo: Sarvier, 2000.
Naw Rocki L, Libersa P, Lambilliotte A et al. Dental anomalies following anticancer chemotherapy. Arch Pediatr 2001; 7: 754-756
