Sedação consciente com Triazolam em Odontologia
Resumo
O Triazolam, quando administrado por via oral, possui um rápido início de ação, duração dos efeitos relativamente curta e boa margem de segurança clínica. Desde que utilizado na dose adequada, torna-se um dos benzodiazepínicos de escolha para a sedação consciente em odontologia. O objetivo deste trabalho
foi apresentar dados relacionados aos parâmetros farmacocinéticos, reações adversas, precauções e contraindicações e posologia do Triazolam, dando suporte ao seu uso na clínica odontológica.
Descritores: Sedação consciente. Triazolam. Odontologia.
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Referências
1. Andrade ED, Ranali J. Emergências médicas em odontologia. 2ª ed. São Paulo: Artes Médicas, 2004.
2. Ranali J. Sedação não é anestesia geral, mas permite um trabalho tranquilo e com segurança. In: Anais do 15º Conclave Odontológico
Internacional de Campinas. 2003; 104:mar/abr. [acesso em 2004 ago 01]. Disponível em: www. acdc.com.br/anais/joseranali.pdf
3. Malamed SF. Sedation: a guide to patient management. Florida: Mosby, 1995.
4. Armonia PL, Tortomano N, Cabral TR, Saraceni- Júnior A. Ansiedade e medo: terapêutica medicamentosa. Rev Odontol Univ Santo Amaro. 2001; 6: 31-4.
5. Felpel LP. Drogas ansiolíticas e relaxantes musculares de ação central. In: Yagiela JA, Neidle EA, Dowd FJ. Farmacologia e terapêutica para dentistas. 4ªed Rio de Janeiro: Guanabara-
Koogan; 2000. p.161-76.
6. United States of Pharmacopeial Convention. Inc. Drug Information for the Heath Care Professional. 17ª ed. Rockville: USP DI, 1997.
7. Greenblatt DJ, Harmatz JS, Engelhardt N, Shader RI. Pharmacokinetic determinants of dynamic differences among three benzodiazepine hypnotics: flurazepam, temazepam, and triazolam. Arch Gen Psychiatry. 1989; 46:326- 32.
8. Kroboth PD, McAuley JW, Kroboth FJ, Bertz RJ, Smith RB. Triazolam pharmacokinetics after intravenous, oral, and sublingual administration. J Clin Psychopharmacol. 1995; 15:259-62.
9. Greenblatt DJ, Harmatz JS, Shapiro L, Engelhardt N, Gouthro TA, Shader RI. Sensitivity to triazolam in the elderly. N Engl J Med. 1991; 324:1691-8.
10. Matear DW, Clarke D. Considerations for the use of oral sedation in the institutionalized geriatric patient during dental interventions: a review of the literature. Spec Care Dentist. 1999; 19: 56-63.
11. Tweedy CM, Milgrom P, Kharasch ED, Kaakko T, Spieker M, Coldwell SE. Pharmacokinetics and clinical effects of sublingual triazolam in pediatric dental patients. J Clin Psychopharmacol.
2001; 21: 268-72.
12. Karl HW, Milgrom P, Domoto P, et al. Pharmacokinetics of oral triazolam in children. J Clin Psychopharmacol. 1997; 17: 169-72.
13. Flanagan, D. Oral triazolam sedation in implant dentistry. J Oral Implantol. 2004; 30: 93-7.
14. Berthold CW, Schneider A, Dionne RA. Using triazolam to reduce dental anxiety. J Am Dent Assoc. 1993; 124: 58-64.
15. Wynn RL, Bergman AS. Reported adverse effects and drug interactions of triazolam (Halcion). Gen Dent. 2004; 52:378-81.
16. Penttilä HJ, Nuutinen LS, Kiviluoma KT, Partanen AM. Sublingual triazolam versus peroral diazepam as a premedication for general
anaesthesia. Can J Anaesth. 1995; 42:862-8.
17. Berthold CW, Dionne RA, Corey SE. Comparison of sublingually and orally administered triazolam for premedication before oral surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.1997;
84: 119-24.
18. Coldwell SE, Awamura K, Milgrom P, et al. Side effects of triazolam in children. Pediatr Dent. 1999; 21:18-25.
19. Pakes GE, Brogden RN, Heel RC, Speight TM, Avery GS. Triazolam: a review of its pharmacological properties and therapeutic
efficacy in patients with insomnia. Drugs. 1981; 22: 81-110.
20. Dionne RA, Kaneko Y. Overcoming pain and anxiety in dentistry. In: Dionne R, Phero JC, Becker DE. Management of pain and anxiety in the dental office. Philadelphia: WB Saunders, 2002. p. 134-5.
21. Ogura C, Nakazawa K, Majima K, et al. Residual effects of hypnotics: triazolam, flurazepam and nitrazepam. Psychopharm. 1980; 68:61-5.
22. Goodchild JH, Dickinson SC. Anxyiolysis in dental practice: a report of three cases. Gen Dent. 2004; 52: 264-8.
23. Quarnstrom FW, Donaldson M. Triazolam use in the dental setting: a report of 270 uses over 15 years. Gen Dent. 2004; 52:496-501.
24. Kaufman E, Hargreaves KM, Dionne RA. Comparison of oral triazolam and nitrous oxide with placebo and intravenous diazepam for
outpatient premedication. Oral Surg Oral Med Oral Pathol. 1993; 75:156-64.
25. Feck AS, Goodchild JH. Reabilitation of a fearful dental patient with oral sedation: Utilizing the incremental oral administration technique. Gen Dent. 2005; 53:22-6.
2. Ranali J. Sedação não é anestesia geral, mas permite um trabalho tranquilo e com segurança. In: Anais do 15º Conclave Odontológico
Internacional de Campinas. 2003; 104:mar/abr. [acesso em 2004 ago 01]. Disponível em: www. acdc.com.br/anais/joseranali.pdf
3. Malamed SF. Sedation: a guide to patient management. Florida: Mosby, 1995.
4. Armonia PL, Tortomano N, Cabral TR, Saraceni- Júnior A. Ansiedade e medo: terapêutica medicamentosa. Rev Odontol Univ Santo Amaro. 2001; 6: 31-4.
5. Felpel LP. Drogas ansiolíticas e relaxantes musculares de ação central. In: Yagiela JA, Neidle EA, Dowd FJ. Farmacologia e terapêutica para dentistas. 4ªed Rio de Janeiro: Guanabara-
Koogan; 2000. p.161-76.
6. United States of Pharmacopeial Convention. Inc. Drug Information for the Heath Care Professional. 17ª ed. Rockville: USP DI, 1997.
7. Greenblatt DJ, Harmatz JS, Engelhardt N, Shader RI. Pharmacokinetic determinants of dynamic differences among three benzodiazepine hypnotics: flurazepam, temazepam, and triazolam. Arch Gen Psychiatry. 1989; 46:326- 32.
8. Kroboth PD, McAuley JW, Kroboth FJ, Bertz RJ, Smith RB. Triazolam pharmacokinetics after intravenous, oral, and sublingual administration. J Clin Psychopharmacol. 1995; 15:259-62.
9. Greenblatt DJ, Harmatz JS, Shapiro L, Engelhardt N, Gouthro TA, Shader RI. Sensitivity to triazolam in the elderly. N Engl J Med. 1991; 324:1691-8.
10. Matear DW, Clarke D. Considerations for the use of oral sedation in the institutionalized geriatric patient during dental interventions: a review of the literature. Spec Care Dentist. 1999; 19: 56-63.
11. Tweedy CM, Milgrom P, Kharasch ED, Kaakko T, Spieker M, Coldwell SE. Pharmacokinetics and clinical effects of sublingual triazolam in pediatric dental patients. J Clin Psychopharmacol.
2001; 21: 268-72.
12. Karl HW, Milgrom P, Domoto P, et al. Pharmacokinetics of oral triazolam in children. J Clin Psychopharmacol. 1997; 17: 169-72.
13. Flanagan, D. Oral triazolam sedation in implant dentistry. J Oral Implantol. 2004; 30: 93-7.
14. Berthold CW, Schneider A, Dionne RA. Using triazolam to reduce dental anxiety. J Am Dent Assoc. 1993; 124: 58-64.
15. Wynn RL, Bergman AS. Reported adverse effects and drug interactions of triazolam (Halcion). Gen Dent. 2004; 52:378-81.
16. Penttilä HJ, Nuutinen LS, Kiviluoma KT, Partanen AM. Sublingual triazolam versus peroral diazepam as a premedication for general
anaesthesia. Can J Anaesth. 1995; 42:862-8.
17. Berthold CW, Dionne RA, Corey SE. Comparison of sublingually and orally administered triazolam for premedication before oral surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.1997;
84: 119-24.
18. Coldwell SE, Awamura K, Milgrom P, et al. Side effects of triazolam in children. Pediatr Dent. 1999; 21:18-25.
19. Pakes GE, Brogden RN, Heel RC, Speight TM, Avery GS. Triazolam: a review of its pharmacological properties and therapeutic
efficacy in patients with insomnia. Drugs. 1981; 22: 81-110.
20. Dionne RA, Kaneko Y. Overcoming pain and anxiety in dentistry. In: Dionne R, Phero JC, Becker DE. Management of pain and anxiety in the dental office. Philadelphia: WB Saunders, 2002. p. 134-5.
21. Ogura C, Nakazawa K, Majima K, et al. Residual effects of hypnotics: triazolam, flurazepam and nitrazepam. Psychopharm. 1980; 68:61-5.
22. Goodchild JH, Dickinson SC. Anxyiolysis in dental practice: a report of three cases. Gen Dent. 2004; 52: 264-8.
23. Quarnstrom FW, Donaldson M. Triazolam use in the dental setting: a report of 270 uses over 15 years. Gen Dent. 2004; 52:496-501.
24. Kaufman E, Hargreaves KM, Dionne RA. Comparison of oral triazolam and nitrous oxide with placebo and intravenous diazepam for
outpatient premedication. Oral Surg Oral Med Oral Pathol. 1993; 75:156-64.
25. Feck AS, Goodchild JH. Reabilitation of a fearful dental patient with oral sedation: Utilizing the incremental oral administration technique. Gen Dent. 2005; 53:22-6.
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Publicado
2016-05-10
Como Citar
Andrade, E. D. de, Pinheiro, M. L. P., & Moreira, A. (2016). Sedação consciente com Triazolam em Odontologia. Arquivos Em Odontologia, 47(2). Recuperado de https://periodicos.ufmg.br/index.php/arquivosemodontologia/article/view/3569
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