Evaluation of the neonatal screening for congenital hypothyroidism in the São José do Rio Preto-SP, Brazil
DOI:
https://doi.org/10.5935/2316-9389.2011.v15.50348Keywords:
congenital hypothyroidism, neonatal screening, newborn, health programs and plansAbstract
Congenital hypothyroidism (CH) is a systemic metabolic disorder characterized by thyroid hormone deficiency at birth and represents one of the most common causes of mental retardation. This research aimed to evaluate the Neonatal Screening Program in São Jose do Rio Preto-SP. Births data were collected from the city’s hospital records. Newborn screening test results from the APAE-SP (Portuguese acronym for Association of Parents and Friends of Mentally Retarded Children, São Paulo branch) files performed between 2005 and 2007 were also used. 17,494 newborn screening results were analyzed. 51.5% were from a female and 48.4% male. Samples were collected after the baby was 7 days old in 62.5% of the cases. The average time to receive the results was 28.2 days. In the studied sample, 14 results were altered, but only five diagnosis were confirmed (incidence rate of 1:3499). Similarly to many of the country’s areas the program in São José do Rio Preto shows major deficiencies as to blood collection time and results processing.Downloads
References
1. Ministério da Saúde.Secretaria Atenção à Saúde.Departamento de Atenção Especializada.Coordenação-Geral de Média Complexidade Ambulatorial. Programa Nacional de Triagem Neonatal. Manual de normas técnicas e rotinas operacionais do Programa Nacional de Triagem Neonatal. Brasília: Ministério da Saúde; 2004. 127 p.
2. De Montalembert M. Management of children with sickle cell anemia: a collaborative work. Arch Pediatr. 2002; 9(11): 1195-201.
3. Neto EC, Rubin R, Schulte J, Guigliani R. Newborn screening for congenital infectious diseases. Emerg Infect Dis. 2004; 10(6): 1068-73.
4. Acharya K, Ackerman PD, Ross LF. Pediatricians’ attitudes toward expanding newborn screening. Pediatr. 2005; 116(4): 476-84.
5. Dhondt JL. Neonatal screening: from the “Guthrie age”to the “Genetic age”. J Inherit Metab Dis. 2007; 30(4): 418-22.
6. Serving the family from birth to the medical home. A report from the Newborn ScreeningTask Force convened inWashington DC, May 10-11, 1999. Pediatr. 2000; 106(2Pt2):383-427.
7. ZaffanelloM,Maffeis C, ZamboniG. Multiple positive results during a neonatal screening program: a retrospective analysis of incidence, clinical implications and outcomes. J Perinat Med. 2005; 33(3): 246-51.
8. Borrajo GJC. Newborn screening in Latin América at the beginning of the 21st century. J Inherit Metab Dis. 2007; 30(4): 466-81.
9. Carvalho TM, dos Santos HP, dos Santos IC, Vargas PR, Pedrosa J. Newborn screening: a national public health programme in Brazil. J Inherit Metab Dis. 2007; 30(4):615.
10. Schmidt BJ,Vargas PR, Martins AM, et al. PKU screening in Brazil. In: New Horizons in neonatal screening, proceedings of the 9th International Neonatal Screening Symposium, and 2nd Meeting of the International SocietyforNeonatal Screening. Lille, France September, 1993. Amsterdam: Elsevier Science/Excerpta Medica; 1994, p. 329-32.
11. Barbosa RLV, Matsumoto MS, Schmidt BJ,Spinola-Castro AM.Aetiology of primary hypothyroidism in São Paulo.T4 Screening Program–APAE– São Paulo. Neonatal Screening in the Nineties. In: 8th International Neonatal Screening Symposium, 1991, Sidney, Austrália; 1991. p. 73-4.
12. Instituto Brasileiro de Geografia e Estatística. Brasília (DF): Ministério do Planejamento, Orçamento e Gestão; 2006. [Citado 2009 maio 18]. Disponível em: http://www.ibge.gpv.br.
13. Ward LS, Maciel RMB, Kunii IS, Kurazawa GK, Matsumura LK, Vieira JGH. Comparação entre duas estratégias para a detecção precoce do hipotiroidismo congênito. Rev Assoc Med Brás. 1998; 44(2): 81-6.
14. Benevides AM, Lima CHV, Rocha CA, Corrêa RR, El Husny AS, Fernandes-Caldato HC. Perfil epidemiológico de portadores de hipotireoidismo congênito. Rev Para Med. 2006; 20(3): 23-6.
15. Radetti G, Zavallone A, Gentrili L, Beck-Peccoz P, Bona G. Foetal and neonatal thyroid disorders. Minerva Pediatr. 2002; 54: 383-400.
16. LaFranchi S. Diagnosis and treatment of hypothyroidism in children. MD. Compr Ther. 1987; 13(10): 20-30.
17. LaFranchi S. Congenital Hypothyroidism: etiologies, diagnosis, and management. Thyroid. 1999; 9(7): 735-40.
18. Silva LO, Dias, VMA, Silva IN, Chagas AJ. Hipotiroidismo congênito transitório: perfil das crianças identificadas no programa estadual de triagem neonatal de Minas Gerais, Brasil. Arq Bras Endocrinol Metab. 2005; 49(4): 521-8.
19. Nascimento ML, Pires MMS, Nassar SM, Ruhland L. Avaliação Do Programa De Rastreamento Neonatal Para Hipotireoidismo Congênito da Secretaria de Estado da Saúde de Santa Catarina. Arq Bras Endocrinol Metab,;47(1):75-81.
20. Ramalho RJR, Ramalho ARO,Oliveira CRP,Aguiar-Oliveira MH. Evolução do Programa de Triagem Neonatal paraoHipotireoidismo Congênito e Fenilcetonúria no Estado de Sergipe de 1995 a 2003. Arq Bras Endocrinol Metab. 2004; 48(6): 890-6.
21. Almeida AM, Godinho TM, Teles MS, et al. Avaliação do Programa de Triagem Neonatal na Bahia no ano de 2003. Rev Bras Saude Mater Infant. 2006; 6(1): 85-91.
22. Carvalho MDB, Pelloso SM, Higarashi IH, Luz GS. Cobertura do Programa de Triagem Neonatal em Maringá (PR), 2001 a 2006. Acta Paul Enferm. 2008; 21(1): 89-93.
Downloads
Published
Issue
Section
License
Copyright (c) 2011 Reme: Revista Mineira de Enfermagem
This work is licensed under a Creative Commons Attribution 4.0 International License.
Links
Facebook
Instagram
Twitter
