Clinical and Microbiological performance of propolis mouth wash in children with active caries
Keywords:
Própolis, Mouthwashes, FluorideAbstract
The objective of the present study was to assess the clinical and microbiological performance of propolis mouth wash in children with active caries. For this, a 0.2% sodium fluoride solution was used as a positive control. The antimicrobiana activity of the propolis extract was carried out in a solid culture medium to determine Minimum Inhibitory Concentration (MIC) using strains of S. mutans. From the extract’s MIC, a 6.25% propolis mouth wash was created. The sample was comprised of 30 children with active caries, between 8 and 10 years of age, divided randomly into: GF - Fluorine Group (Control) and PG - Propolis Group. Indices of dental biofilm (IHOS and PHP) and gengival illnesses (ISG, IG), as well as the S Mutans count from the saliva sample were collected. before (In-initial) and 24 hours after (Fn-end) the 15th application of the mouth washes. The results presented values for In and Fn: (1) for GF: IHOS 2.4/2.0; PHP 0.88/079; IG 0.34/0.11; ISG 13.22/9.15; and UFC/ml 5.05x10 ² /4.81x10 ² and (2) for GP: IHOS 2.0/1.86; PHP 0.77/0.65; IG 0.44/ 0.37; ISG 22.31/13.48; and UFC/ml 9.41x 10 ² /2.09x
10 ². The difference between In and Fn for GF obtained statistical significance by means of the t test for IG (p< 0.01), ISG (p<0.05), PHP (p<0.01), IHOS
(p<0.01), whereas for GP the same was obtained for ISG (p<0.05), PHP (p<0.05), UFC/ml (p<0.05).
In the crisscrossing of GF (Controle) with GP, only the UFC/ml (p<0,05) obtained a statistical significance. It could therefore be concluded that the isolated performance of the tested mouth washes was effective, observing a subsequent equivalence in the clinical markers. Furthermore, only the GP presented a significant reduction in the UFC/ml levels of S. mutans from saliva.
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