Putting animal parts into humans: a political analysis

Johannes Kögel

doi:10.53981/destrocos.v6i2.61076

Autores

Johannes Kögel Otto-von-Guericke University Magdeburg https://orcid.org/0000-0002-2103-4643

DOI:

https://doi.org/10.53981/destrocos.v6i2.61076

Palavras-chave:

biopolítica, xenotransplante, animais, humanização

Resumo

Os papéis dos animais—particularmente porcos e primatas não humanos—na xenotransplantação revelam dinâmicas éticas e simbólicas complexas. Os primatas não humanos, devido à sua proximidade cognitiva com os seres humanos, passaram progressivamente a ser posicionados como receptores e não como fontes de órgãos, refletindo um “upgrade hierárquico” ético. Os porcos, geneticamente modificados para fornecer órgãos, encarnam um status ambíguo: altamente alienados pela manipulação biotecnológica e pelo confinamento estéril, como “biocapital” mercantilizado e inserido em lógicas de mercado. A sua “humanização”, além de uma alteração genética, também implica ocupar o lugar de humanos, embora em um papel diferente do desempenhado pelos primatas. A conotação ética disso pode beneficiar esses animais a longo prazo. Reconhecer a alteridade animal—não apenas como corpos biológicos, mas como sujeitos intencionais—como, por exemplo, sugerido pela metafísica ameríndia, reformula a compreensão da identidade e da prática médica em meio a concepções moleculares e semióticas da vida. Essas considerações demandam uma reflexão mais nuançada sobre as fronteiras entre natureza, cultura e espécie na biomedicina contemporânea.

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Biografia do Autor

Johannes Kögel, Otto-von-Guericke University Magdeburg

Johannes Kögel, a philosopher and sociologist by training, has conducted research and published works on migration, postcolonial sociology, and biotechnologies—particularly brain-computer interfaces and xenotransplantation. He is the author of the monograph Navigating Nationality and currently serves as a Research Associate in Germany.

Referências

AGENCE FRANCE-PRESSE. A US farm breeds pigs for human kidney transplants. 17 Dec. 2024. Available in: https://www.france24.com/en/live-news/20241217-a-us-farm-breeds-pigs-for-human-kidney-transplants. Last access: 27 Jul. 2025.

ALI, Asghar et al. What genetic modifications of source pigs are essential and sufficient for cell, tissue, and organ xenotransplantation? Transplant International, v. 37, e13681, 2024. DOI: https://doi.org/10.3389/ti.2024.13681

BASTIAN, Brianna et al. Don't mind meat? The denial of mind to animals used for human consumption. Personality and Social Psychology Bulletin, v. 38, n. 2, p. 247-256, 2012. DOI: https://doi.org/10.1177/0146167211424291

BENNINGSTAD, Nina C. G.; KUNST, Jeroen R. Dissociating meat from its animal origins: A systematic literature review. Appetite, v. 147, p. e104554, 2020. DOI: https://doi.org/10.1016/j.appet.2019.104554

BROWN, Keith. UAB Experimenters Perform Unauthorized Surgeries, Falsify Records. Peta, 9 Jun. 2022. Available in: https://www.peta.org/news/uab-experimenters-perform-unauthorized-surgeries-falsify-records/. Last access: 01 Ago. 2025.

BROWN, Nik. Xenotransplantation: normalizing disgust. Science as Culture, v. 8, n. 3, p. 327–355, 1999. DOI: https://doi.org/10.1080/09505439909526550

CARR, Ray. Species of contagion. Animal-to-human transplantation in the age of emerging infectious disease. Singapore: Palgrave Macmillan, 2022. DOI: https://doi.org/10.1007/978-981-16-8289-6

CAVALIERI, Paola; SINGER, Peter (eds.). The Great Ape Project. Equality beyond humanity. London: Fourth Estate, 1993.

CHARTERS, Jacob D. The importance of storytelling in shaping attitudes towards jaguars (Panthera onca) and parallels with folklore of non-indigenous traditional communities of the Central Amazon Basin. 2019. Tese (Doutorado) – Universidade de São Paulo, São Paulo, 2019.

CHRULEW, Matthew. Animals as biopolitical subjects. In: CHRULEW, Matthew; WADIWEL, Dinesh J. (eds.). Foucault and animals. Leiden: Brill, 2017. p. 222-238. DOI: https://doi.org/10.1163/9789004332232_011

CIMATTI, Felice; SALZANI, Carlo (eds.). The biopolitical animal. Edinburgh: Edinburgh University Press, 2024. DOI: https://doi.org/10.3366/edinburgh/9781399525985.001.0001

COOK, Peta S. Science Stories. Selecting the source animal for xenotransplantation. Social Change in the 21st Century 2006 Conference Proceedings. Queensland University of Technology, 2006.

COOK, Peta S.; OSBALDISTON, Nicholas. Pigs hearts and human bodies: A cultural approach to xenotransplantation. M/C Journal, v. 13, n. 5, 2010. DOI: https://doi.org/10.5204/mcj.283

COOPER, David K. C. Advancing xenotransplantation to the clinic: How relevant is the pig-to–nonhuman primate kidney transplantation model today? Transplantation, v. 106, n. 9, p. 1717-1719, 2022. DOI: https://doi.org/10.1097/TP.0000000000004097

DARIO, Fabio R. Fantastic entities of the Amazonian indigenous culture. World News of Natural Sciences, v. 50, p. 159-177, 2023.

DATA BRIDGE MARKET RESEARCH. Unlocking the Future of Medicine: Exploring the Science and Ethics of Xenotransplantation in Healthcare. Oct, 04 2023. Available in: https://www.databridgemarketresearch.com/news/global-xenotransplantation-market. Last access: 29 Jul. 2025.

DEPARTMENT OF HEALTH (UK). Animal tissue into humans. A report by the Advisory Group on the Ethics of Xenotransplantation. London: HMSO, 1997.

DESCHAMPS, Jack-Yves et al. History of xenotransplantation. Xenotransplantation, v. 12, n. 2, p. 91–109, 2005. DOI: https://doi.org/10.1111/j.1399-3089.2004.00199.x

DESCOLA, Philippe. Beyond nature and culture. Chicago, IL: University of Chicago Press, 2013. DOI: https://doi.org/10.7208/chicago/9780226145006.001.0001

DOUGLAS, Mary. Purity and danger. London: Routledge and Keegan Paul, 1976.

ESPOSITO, Roberto. The third person. Cambridge, MA: Polity Press, 2012.

FAO. World food and agriculture: statistical yearbook 2024. Rome, 2024.

FAUSTO, Carlos. Feasting on people: eating animals and humans in Amazonia. Current Anthropology, v. 48, n. 4, p. 497-530, 2007. DOI: https://doi.org/10.1086/518298

FOUCAULT, Michel. Society must be defended. Lectures at the Collège de France, 1975-1976. London: Allen Lane, 2003.

GIELING, Elly T.; NORDQUIST, Reinette E.; VAN DER STAAY, Frans J. Assessing learning and memory in pigs. Animal Cognition, v. 14, p. 151–173, 2011. DOI: https://doi.org/10.1007/s10071-010-0364-3

HADDOW, Gill. Embodiment and everyday cyborgs. Technologies that alter subjectivity. Manchester: Manchester University Press, 2021. DOI: https://doi.org/10.7765/9781526114198

HANSSON, Kristofer. The reconfigured body. Human-animal relations in xenotransplantation. Kulturstudier, v. 2, n. 2, p. 142-156, 2011. DOI: https://doi.org/10.7146/ks.v2i2.5791

HARAWAY, Donna. A manifesto for cyborgs: science, technology, and socialist feminism. Socialist Review, n. 80, p. 65-108, 1985.

HARAWAY, Donna. When species meet. Minneapolis; London: University of Minnesota Press, 2008.

HASLAM, Nick; LOUGHNAN, Steve; HOLLAND, Elise. The psychology of humanness. In: GERVAIS, Sarah J. (ed.). Objectification and (de)humanization. New York: Springer, 2013. p. 25-51. DOI: https://doi.org/10.1007/978-1-4614-6959-9_2

HAUSER, Marc et al. Challenges and opportunities in cell expansion for cultivated meat. Frontiers in Nutrition, v. 11, 1315555, 2024. DOI: https://doi.org/10.3389/fnut.2024.1315555

JASANOFF, Sheila; KIM, Sang-Hyun. Containing the atom: sociotechnical imaginaries and nuclear power in the United States and South Korea. Minerva, v. 47, n. 2, p. 119–146, 2009. DOI: https://doi.org/10.1007/s11024-009-9124-4

KIRK, Robert G. W. The birth of the laboratory animal: biopolitics, animal experimentation, and animal wellbeing. In: CHRULEW, Matthew; WADIWEL, Dinesh J. (eds.). Foucault and animals. Leiden: Brill, 2017. p. 191-221. DOI: https://doi.org/10.1163/9789004332232_010

KÖGEL, Johannes et al. Engineering organs, hopes and hybridity: considerations on the social potentialities of xenotransplantation. Medical Humanities, v. 51, n. 1, p. 180-184, 2025. DOI: https://doi.org/10.1136/medhum-2024-013061

KOHN, Eduardo. How forests think: toward an anthropology beyond the human. Berkeley, CA: University of California Press, 2013. DOI: https://doi.org/10.1525/9780520956865

KOPLIN, Julian J. 'It’s not worse than eating them': the limits of analogy in bioethics. Monash Bioethics Review, v. 38, n. 2, p. 129–145, 2020. DOI: https://doi.org/10.1007/s40592-020-00115-z

LATOUR, Bruno. Give me a laboratory and I will raise the world. In: KNORR-CETINA, Karin; MULKAY, Michael (eds.). Science observed. London: Sage, 1983. p. 141–170.

LATOUR, Bruno. We have never been modern. Cambridge, MA: Harvard University Press, 1993.

LEI, Tao et al. Genetic engineering of pigs for xenotransplantation to overcome immune rejection and physiological incompatibilities: the first clinical steps. Frontiers in Immunology, v. 13, p. e1031185, 2022. DOI: https://doi.org/10.3389/fimmu.2022.1031185

LEMKE, Thomas. Biopolitics. An advanced introduction. New York, NY: New York University Press, 2011.

LÉVI-STRAUSS, Claude. A lesson in wisdom from mad cows. In: LÉVI-STRAUSS, Claude. We are all cannibals: and other essays. New York: Columbia University Press, 2013. p. 112-119. DOI: https://doi.org/10.7312/columbia/9780231170680.003.0014

LÉVI-STRAUSS, Claude. We are all cannibals. In: LÉVI-STRAUSS, Claude. We are all cannibals: and other essays. New York: Columbia University Press, 2013. p. 83-89. DOI: https://doi.org/10.7312/columbia/9780231170680.003.0010

LOUGHNAN, Sarah; HASLAM, Nick; BASTIAN, Brianna. The role of meat consumption in the denial of moral status and mind to meat animals. Appetite, v. 55, n. 1, p. 156–159, 2010. DOI: https://doi.org/10.1016/j.appet.2010.05.043

LUNDIN, Susanne. Creating identity with biotechnology: the xenotransplanted body as the norm. Public Understanding of Science, v. 11, n. 4, p. 333–345, 2002. DOI: https://doi.org/10.1088/0963-6625/11/4/302

LUNDIN, Susanne. The boundless body: cultural perspectives on xenotransplantation. Ethnos, v. 64, n. 1, p. 5–31, 1999. DOI: https://doi.org/10.1080/00141844.1999.9981588

MALLAPATY, Smriti; KOZLOV, Max. The science behind the first pig-organ transplant trial in humans. Nature, 04 Feb. 2025. Available in: https://www.nature.com/articles/d41586-025-00368-w. Last access: Ago. 01, 2025.

MARINO, Lori; COLVIN, Christine M. Thinking pigs: a comparative review of cognition, emotion, and personality in Sus domesticus. International Journal of Comparative Psychology, v. 28, 2015. DOI: https://doi.org/10.46867/ijcp.2015.28.00.04

MOU, Liang; PU, Zhengrong; COOPER, David K. C. Clinical xenotransplantation of gene-edited pig organs: a review of experiments in living humans since 2022. Medicine Bulletin, v. 1, p. 77-85, 2025. DOI: https://doi.org/10.1002/mdb2.70003

NUFFIELD COUNCIL ON BIOETHICS. Animal-to-human transplants: the ethics of xenotransplantation. London: Nuffield Council on Bioethics, 1996.

OECD. The bioeconomy to 2030. Designing a policy agenda. Paris: OECD, 2006.

OECD/FAO. OECD-FAO agricultural outlook 2025-2034. Paris; Rome: OECD Publishing; FAO, 2025.

PETERSON, Lisa et al. Physiological basis for xenotransplantation from genetically modified pigs to humans. Physiological Reviews, v. 104, n. 3, p. 1409-1459, 2024. DOI: https://doi.org/10.1152/physrev.00041.2023

ROTHGERBER, Haley. Meat-related cognitive dissonance: a conceptual framework for understanding how meat eaters reduce negative arousal from eating animals. Appetite, v. 146, 104511, 2020. DOI: https://doi.org/10.1016/j.appet.2019.104511

SHARP, Lesley A. Monkey business: interspecies longing and scientific prophecy in experimental xenotransplantation. Social Text, v. 29, n. 1, p. 43–69, 2011. DOI: https://doi.org/10.1215/01642472-1210265

SHARP, Lesley A. The transplant imaginary. Mechanical hearts, animal parts, and moral thinking in highly experimental science. California: University of California Press, 2014. DOI: https://doi.org/10.1525/california/9780520277960.001.0001

SINGER, Peter. Practical ethics. Cambridge: Cambridge University Press, 1993.

SPARROW, Richard. Xenotransplantation, consent and international justice. Developing World Bioethics, v. 9, n. 3, p. 119–127, 2009. DOI: https://doi.org/10.1111/j.1471-8847.2009.00251.x

SUNDER RAJAN, Kaushik. Biocapital: the constitution of postgenomic life. Durham: Duke University Press, 2006. DOI: https://doi.org/10.1515/9780822388005

SYKES, Megan; D’APICE, Anthony; SANDRIN, Mauro. Position paper of the Ethics Committee of the International Xenotransplantation Association. Xenotransplantation, v. 10, n. 3, p. 194–203, 2003. DOI: https://doi.org/10.1034/j.1399-3089.2003.00067.x

VASUDEV, Kannan; COOPER, David K. C. How much will a pig organ transplant cost? A preliminary estimate of the cost of xenotransplantation versus allotransplantation in the USA. Xenotransplantation, v. 32, n. 1, e70018, 2025. DOI: https://doi.org/10.1111/xen.70018

VIDAL DE BATTINI, Berta Elena. Cuentos y leyendas populares de la Argentina. Tomo 8. Buenos Aires: Ediciones Culturales Argentinas, 1984.

VIVEIROS DE CASTRO, Eduardo. Cannibal metaphysics. Minneapolis, MN: Univocal Publishing, 2014.

WADIWEL, Dinesh. The war against animals. Leiden: Brill, 2015. DOI: https://doi.org/10.1163/9789004300422

WATSON, Lyall. The whole hog: exploring the extraordinary potential of pigs. Washington: Smithsonian Books, 2004.

WOLF, Eckhard et al. Designer pigs for xenogeneic heart transplantation and beyond. Disease Models & Mechanisms, v. 16, n. 5, 2023. DOI: https://doi.org/10.1242/dmm.050177

WOLFE, Cary. Before the law: humans and other animals in a biopolitical frame. Chicago: University of Chicago Press, 2012. DOI: https://doi.org/10.7208/chicago/9780226922423.001.0001