Púrpura trombocitopênica idiopática
importância do cirurgião-dentista no diagnóstico
Palavras-chave:
Púrpura trombocitopênica idiopática, DiagnósticoResumo
Esse trabalho descreve um caso de púrpura trombocitopênica idiopática (PTI) diagnosticado durante exame odontológico de rotina. A PTI é uma desordem caracterizada pela destruição anormal das plaquetas circulantes e geralmente apresenta manifestações bucais. Dessa forma, destacamos a importância de o cirurgião-dentista estar apto a reconhecer os sinais e sintomas da PTI, principalmente mudanças bucais que não têm origem dental, possibilitando tratamento imediato. Esta patologia quando não tratada, pode ser irreversível e fatal.
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Referências
Themistocleous E, Ariyaratnam S, Duxbury AJ. Acute idiopathic thrombocytopenic purpura: a case report. Dent Update. 2004; 31:92-6.
Levine SP. Wintrobe’s clinical hematology. Philadelphia: Willians & Wilkins, 1999.
Sonis ST, Fazio RC, Fang L. Princípios e prática de medicina oral. 2ªed. Rio de Janeiro: Guanabara Koogan, 1996.
Yeager DA. Idiopathic thrombocytopenic purpura: report of case. J Am Dent Assoc. 1975; 90:640-3.
Wintrobe MM, Lee DR, Boggs DR et al. Clinical hematology. 8ªed. Philadelphia: Lea & Febiger, 1981.
Blanchette V, Carcao M. Approach to the investigation and management of immune thrombocytopenic purpura in children. Semin Hematol. 2000; 37:299-314.
George JN, Woolf SH, Raskob GE et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology Blood. 1996; 88:3-40.
Ben-Yehuda D, Gillis S, Eldor A. Clinical and therapeutic experience in 72 israeli patients with idiopathic thrombocytopenic purpura. Acta Haematol. 1994; 91:1-6.
Imbach P, Kühne T. Immune thrombocytopenic purpura ITP. Vox Sang. 1998; 74:309-14.
James WD, Guiry CC, Grote WR. Acute idiopathic thrombocytopenic purpura. Oral Surg Oral Med Oral Pathol. 1984; 57:149-51.
Cortelazzo S, Finazzi G, Buelli M, Molteni A, Viero P, Barbui T. High risk of severe bleeding in aged patients with chronic idiopathic thrombocytopenic purpura. Blood. 1991; 77:31- 3.
Cohen YC, Djulbegovic B, Shamai-Lubovitz O, Mozes B. The bleeding risk and natural history of idiopathic thrombocytopenic purpura in patients with persistent low platelet counts. Arch Intern Med. 2000; 160:1630-8.
Guyton AC, Hall JE. Fisiologia humana e mecanismos das doenças. 6ªed. Rio de Janeiro: Guanabara Koogan, 1998.
Hunter ML, Hunter B, Lesser S. Acute idiopathic thrombocytopenic purpura in childhood: report of a case presenting in general dental practice. Br Dent J. 1997; 183:27-9.
Chong BH, Keng TB. Advances in the diagnosis of idiopathic thrombocytopenic purpura. Semin Hematol. 2000; 37:249-60.
Leung AYH, Chim CS, Kwong YL, Lie AKW, Au WY, Liane R. Clinicopathologic and prognostic features of chronic idiopathic thrombocytopenic purpura in adult chinese patients: an analysis of 220 cases. Ann Hematol. 2001; 80:384-6.
Mcmillan R. Chronic idiopathic thrombocytopenic purpura. N Engl J Med. 1981; 304: 1135-47.
Fantasia JE, Damm DD. Oral diagnosis – mucosal hemorrhage – thrombocytopenia purpura. Gen Dent. 2002; 50:82-4.
Fotos PG, Graham WL, Bowers DC, Perfetto SP. Chronic autoimmune thrombocytopenic purpura: a 3-year case study. Oral Surg Oral Med Oral Pathol. 1983; 55:564-7.
Mcmillan R. The pathogenesis of chronic immune (idiopathic) thrombocytopenic purpura. Semin Hematol. 2000; 37:5-9.
Schramm A, Schon R, Gellrich NC. Therapy refractory idiopathic thrombocytopenia. Contraindication for dental surgery interventions. Mund Kiefer Gesichtschir. 1999; 3:43-5.
Bouroncle BA, Doan CA. Treatment of refractory idiopathic thrombocytopenic purpura. J Am Dent Assoc. 1969; 207:2049-52.
Laros Junior RK, Penner JA. Refractory thrombocytopenic purpura treated successfully with cyclophosphamide. J Am Dent Assoc. 1971; 215:445-9.
George JN. Treatment options for chronic idiopathic (immune) thrombocytopenic purpura. Semin Hematol. 2000; 37:31-4.
Mazzucconi MG, Arista MC, Peraio M et al. Long-term follow up of autoimmune thrombocytopenic purpura (ATP) patients submitted to splenectomy. Eur J Haematol. 1999; 62:219-22.
Syracuse EP. Purpura: a review. J Oral Med. 1975; 30:21-3.