ORAL SEQUELAE IN CHILDREN SUBMITTED TO THE ANTINEOPLASTIC THERAPY
CAUSES AND DEFINITION OF THE DENTAL SURGEON’S ROLE
Keywords:
Oral health, Children, CancerAbstract
Immune-suppressed children, such as cancer patients, require dental accompaniment that is integrated with medical care, as numerous oral conditions emerge as a result of the antineoplasic therapy. The aim of the present study was to carry out a bibliographic review on the most frequent oral alterations among children with cancer and on the possible causes for these alterations, as well as to define the dental surgeon’s role in this process. The most frequent oral sequelae due to cancer in children are xerostomia, mucositis, candidiasis and caries, all resulting from radiotherapy and/or chemotherapy. The participation of a dental surgeon, along with a multi- discipline team that treats these patients, is of great importance in the prevention and control of oral sequelae.
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References
Precioso VC, Esteves ARF, Souza AM, Dib LL . Complicações orais na quimioterapia em oncologia pediátrica: o papel da odontologia preventiva. Acta Oncol Bras 1994; 14: 147-152.
Lucas VS, Beighton D, Roberts GJ, Challacombe SJ. Changes in the oral streptococcal flora of children undergoing allogeneic bone marrow transplantation. J Infect 1997; 35: 135-141.
Fleming P, Kinirons MJ. Study of the dental health of children in remission from acute lymphoblastic leukaemia in Northen. Community Dent Oral Epidemiol 1993; 21: 309-312.
Pajari U, Ollila P, Lanning M. Incidence of dental caries in children with acute lymphoblastic leukemia is relates to the therapy used. ASDC J Dent Child 1995, 62: 349-352.
Sepet E, Aytepe Z, Ozerkan AG, Yalman N, Guven Y, Anak S, Devecioglu O, Agaoglu L, Gedikoglu G. Acute lymphoblastic leukemia: dental health of children in maintenance therapy. J Clin Pediatr Dent 1998; 22: 257-260.
Santos VI, Anbinder AL, Cavalcante ASR. Leucemia no paciente pediátrico: atuação odontológica. Cienc Odontol Bras 2003; 6: 49-57.
Minicucci EM, Dib LL, Curi MM, Shinohara EH, Sêneda LM. Seqüelas odontológicas do tratamento rádio e quimioterápico em crianças. Rev Paul Pediatr 1994; 12: 258-263.
Caielli C, Martha PM, Dib LL. Seqüelas orais da radioterapia: atuação da odontologia na prevenção e tratamento. Rev Bras Cancerol 1995; 41: 231- 241.
Dens F, Boogaerts M, Boute P, Declerck D, Demuynck H, Vinckier F. Caries- related salivary microorganisms and salivary flow rate in bone marrow recipients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996; 81: 38- 43.
Dahllöf G, Modéer T, Bolme P, Ringdén O, Heimdahl A. Oral health in children treated with bone marrow transplantation: a one-year follow-up. ASDC J Dent Child 1988; 55:196-200.
Harrison JS, Dale RA, Haveman CW, Redding SW. Oral complications in radiation therapy. Gen Dent 2003; 51: 552-560.
Heimdahl A, Johson G, Danielsson KH, Lönnqvist B, Sundelin P, Ringden O. Oral conditions of pacients with leukemia and severe aplastic anemia: follow-up 1 year after bone marrow transplantation. Oral Surg Oral Med Oral Pathol 1985; 60: 498-504.
Clarkson JE, Eden OB. Dental health in children with cancer. Arch Dis Child 1998; 78: 560-561.
Jensen SB, Pedersen AM, Reibel J, Nauntofte B. Xerostomia and hypofunction of the salivary glands in cancer therapy. Support Care Cancer 2003; 11: 207-225.
Caribé-Gomes F, Chimenos-Küstner E, López-López J, Finestres-Zubeldia F, Guix-Melcior B. Manejo odontológico de las complicaciones de la radioterapia y quimioterapia en el cáncer oral. Med Oral 2003; 8: 178-187.
Belfield PM, Dwyer AA. Oral complications of childhood câncer and its treatment: current best practice. Eur J Cancer 2004; 40: 1035-1041.
Wiseman M. The treatment of oral problems in the palliative patient. J Can Dent Assoc 2006; 72: 453-458.
Barker GJ, Epstein JB, Williams KB, Raber-Durlacher JE. Current practice and knowledge of oral care for cancer patients: a survey of supportive health care providers. Support Care Cancer 2005; 13:32-41.
