The present work intends to investigate the cultural mediations established at the Centro Cultural Ouvidor 63, a cultural center run in a squatted building located in the center of São Paulo (Brazil) since 2014. It hosts a mixed collective of artists from different origins, languages and performance styles, who share the space for creative, artistic and social experiences. In order to achieve that, this research is based on a number of guiding intersections that crosses the universe of Ouvidor 63, namely: social movements and contemporary insurrections; political art and artivism as an aesthetic-political response to the established system; the perspective of the right to the city and right to the culture incited by artistic squats; and the relations between these artivist mediations, the post-modern cities and cultural diversity. In this process it was possible to observe peculiar and potent characteristics of art and culture in relation to social movements, especially squats. Such insurgent movements reflect contemporary forms of resistance, organization and action developed in the world of art, aesthetics and subjectivities.