Effectiveness of antimicrobian action of jataí bee (Tetragonisca angustula) propolis extract in Gram-positive and Gram-negative bacteria

Abstract

Propolis is produced by bees and corresponds to a material derived from the collection of resinous plant secretions, with the addition of salivary enzymes and wax in the final product composition. Propolis is attributed several biological properties, among them a potential for antimicrobial activity that has been It has been widely studied, since the discovery of antibacterial active ingredients has brought significant advances in healthcare. The present work aimed to evaluate the antimicrobial efficacy of six different concentrations of Jataí bee propolis extract in Gram-positive and Gram-negative bacteria. Twenty propolis samples were collected from meliponaria located in Uchoa-SP and Tabapuã. SP from December 2018 to March 2019. Hydroethanolic extract showed antimicrobial effectiveness against the Gram-positive and Gram-negative microorganisms tested, where E. coli and P. aeruginosa were sensitive to four of the six concentrations and to MIC was 125 µg / mL, whereas K. pneumoniae showed higher sensitivity among Gram-negative strains, as well as the three Gram-positive bacteria, had growth inhibition by five of the tested concentrations and MIC of 62.5 µg / mL. Thus, it was concluded that the hydroethanolic extract of Jataí bee propolis presented substances capable of inhibiting the growth of all bacteria tested and the low MIC values indicate a promising possibility of using this biological material as an alternative to the use of antibiotics. for reducing microbial resistance.