Dental caries in children and adolescents with type 1 Diabetes
systematic review and meta-analysis
DOI:
https://doi.org/10.35699/2178-1990.2021.27061Keywords:
Dental caries, Diabetes mellitus, Child, Adolescent, Review, Meta-analysis as topicAbstract
Aim: The aim of this systematic review and meta-analysis was to evaluate studies in which children/adolescents with type 1 Diabetes (DM1) were compared with children/adolescents without DM1 as regards dental caries.
Methods: Electronic searches in Web of Science, Scopus, Lilacs, PubMed, OpenGrey, and Google Scholar databases were conducted up to December/2020. Study selection was carried out separately by two reviewers. References that met the eligibility criteria were included. Risk of bias was evaluated using the Newcastle Ottawa scale. Meta-analyses were conducted. Mean difference (MD) and confidence intervals (CI) were provided.
Results: In the database searches, 751 references were retrieved. Following the removal of 102 duplicates, 649 references were assessed, and 16 studies were included in this systematic review and meta-analysis. Discrepancies in results were found among the included studies. Two meta-analyses demonstrated no significant difference between children/adolescents with DM1 and children/adolescents without DM1 regarding the mean number of permanent teeth with caries (MD = 0.07; CI = -0.68 – 0.82), as well as no significant difference between children/adolescents with DM1 and children/adolescents without DM1 with respect to the mean number of permanent tooth surfaces with caries (MD = 0.20; CI = -2.22 – 2.61). The third meta-analysis revealed that children/adolescents without DM1 had a significantly higher mean number of primary teeth with caries in comparison to children/adolescents with DM1 (MD = 0.34; CI = 0.31 – 0.37). The major issues in the risk of bias assessment were the definition of controls and comparison between cases and controls.
Conclusion: The occurrence of caries seems to be lower in children/adolescents with DM1 than in children/adolescents without DM1.
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References
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