Miconia albicans (Sw.) Triana (canela-de-velho), the new trend plant from the Brazilian Cerrado

contribution to species identification and pharmacological aspects

Authors

  • Diego Tavares Iglesias Universidade Federal de Minas Gerais. Montes Claros, MG. Brasil.
  • Rúbia Santos Fonseca Universidade Federal de Minas Gerais. Montes Claros, MG. Brasil. https://orcid.org/0000-0001-7257-874X

DOI:

https://doi.org/10.35699/2447-6218.2022.38438

Keywords:

Medicinal plant, Phytotherapy, Taxonomy, Melastomataceae

Abstract

Miconia albicans (canela-de-velho) is a species widely distributed in the Cerrado. In recent years, its leaves have been commercialized for the preparation of medicinal teas. The genus Miconia is highly diverse in the Cerrado, and the high morphological similarity of the species often results in misidentification, even by specialists. The aim of this paper is to contribute to the identification of M. albicans, and its distinction from other Cerrado species with morphological similarity. In addition, a literature review of the species was performed in search of studies on potential biological and pharmacological activity. Nineteen samples of plants marketed as "canela-de-velho" and/or Miconia albicans were acquired from fairs in six municipalities in Minas Gerais, Brazil. The species were properly identified and conflicting characters were determined. Based on these characters, a survey of all species with morphological similarity in Cerrado was carried out. Thirteen species similar to M. albicans were found, and an illustrated identification key was developed. As for the review of biological activity, only M. albicans presents anti-inflammatory activity identified by one study. M. albicans and six of the 13 identified species showed cytotoxicity at high concentration levels in studies with in vitro and in vivo analyses. M. albicans accumulates aluminum in the leaves, which are the organs used to prepare the infusion. Currently, there are no clinical trials to validate the use of M. albicans as herbal medicine.  Indiscriminate use and lack of scientific evidence, besides not producing the desired results, can cause adverse effects.

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References

Albuquerque, U. P.; Hanazaki, N. 2006. As pesquisas etnodirigidas na descoberta de novos fármacos de interesse médico e farmacêutico: fragilidades e pespectivas. Brazilian Journal of Pharmacognosy, 16: 678-689. Doi: https://doi.org/10.1590/S0102-695X2006000500015.

Almeida, M. Z.; Léda, P. H. O.; Silva, M. Q. O. R.; Pinto, A.; Lisboa, M.; Guedes, M. L. M. L.; Peixoto, A. L. 2014. Species with medicinal and mystical-religious uses in São Francisco do Conde, Bahia, Brazil: a contribution to the selection of species for introduction into the local Unified Health System. Brazilian Journal of Pharmacognosy 4: 171-184. Doi: https://doi.org/10.1016/j.bjp.2014.04.006.

Andrade e Silva, M. L.; Cunha, W. R.; Pedro, C.; Aparecida Garcia, P.; Martins, C. 2002. Evaluation of the analgesic activity of an ethanol extract of Miconia fallax. Bollettino Chimico Farmaceutico, 141: 158-160.

ANVISA - Agência Nacional de Vigilância Sanitária. 2016. Memento Fitoterápico. Brasília, ANVISA. Available from: https://www.gov.br/anvisa/pt-br/assuntos/farmacopeia/formulario-fitoterapico/MementoFitoterapico1.pdf

Araújo, I. M.; Romero, R. 2016. A tribo Miconieae (Melastomataceae) no Parque Estadual do Biribiri, Diamantina, Minas Gerais, Brasil. Rodriguésia, 67: 953-970. Doi: https://doi.org/10.1590/2175-7860201667407.

BFG - The Brazil Flora Group. 2015. Growing knowledge: an overview of seed plant diversity in Brazil. Rodriguésia, 66: 1085-1113. Doi: https://doi.org/10.1590/2175-7860201566411.

Bochner, R.; Fiszon, J. T.; Assis, M. A.; Avelar, K. E. S. 2012. Problemas associados ao uso de plantas medicinais comercializadas no Mercadão de Madureira, município do Rio de Janeiro, Brasil. Revista Brasileira de Plantas Medicinais, 14: 537-547. Doi: https://doi.org/10.1590/s1516-05722012000300017.

Bondy, S. C. 2016. Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration. Neurotoxicology, 52: 222-229. https://doi.org/10.1016/j.neuro.2015.12.002.

Bussmann, R. W.; Sharon, D. 2006. Traditional medicinal plant use in Northern Peru: tracking two thousand years of healing culture. Journal of Ethnobiology and Ethnomedicine, 2: 47.

Caddah, M. K.; Goldenberg, R. 2013. Miconia atlantica, a new species of Melastomataceae from the eastern mountains of Brazil. Brittonia, 65: 351-356. Doi: https://doi.org/10.1186/1746-4269-2-47.

Candido, C. P. 2005. A família Melastomataceae na Serra do Cabral: tribos Melastomeae, Merianieae e Miconieae. Campinas: Universidade Estadual de Campinas, 99f. Dissertação de Mestrado. Available from: tinyurl.com/2p8ufjky.

Celotto, A. C.; Nazario, D. Z.; Spessoto, M. A.; Martins, C. H. G.; Cunha, W. R. 2003. Evaluation of the in Vitro Antimicrobial Activity of Crude Extracts of Three Miconia Species. Brazilian Journal of Microbiology, 34: 339-340. Doi: https://doi.org/10.1590/s1517-83822003000400010.

Cogniaux, A. 1887/1888. Miconia, Melastomataceae. p. 212-424. In: Martius, C.F.P.; Eichler, A.G., eds. Flora Brasiliensis, 14(4). Frid. Fleischer, Lipsiae. Available from: tinyurl.com/4evberbj.

Coulaud-Cunha, S.; Oliveira, R. S.; Waissmann, W. 2004. Venda livre de Sorocea bomplandii Bailon como Espinheira Santa no município do Rio de Janeiro-RJ. Brazilian Journal of Pharmacognosy, 14: 51-53. Doi: https://doi.org/10.1590/s0102-695x2004000300019.

Crepaldi, M. O. S.; Peixoto, A. L. 2010. Use and knowledge of plants by “Quilombolas” as subsidies for conservation efforts in an area of Atlantic Forest in Espírito Santo State, Brazil. Biodiversity and Conservation, 19: 37-60. Doi: https://doi.org/10.1007/s10531-009-9700-9.

Cruz, A. V. M.; Kaplan, M. A. C. 2004. Uso medicinal de espécies das famílias Myrtaceae e Melastomataceae no Brasil. Floram, 11: 47-52. Available from: tinyurl.com/yckj8wr7.

Cunha, W. R.; Martins, C.; Ferreira, D. S.; Crotti, A. E. M.; Lopes, N. P.; Albuquerque, S. 2003. In vitro trypanocidal activity of triterpenes from Miconia species. Planta Medica, 69: 470-472. Doi: https://doi.org/10.1055/s-2003-39719.

Dias, J. E.; Laureano, L. C. 2010. Farmacopéia popular do cerrado. Goiás, Articulação Pacari.

Forzza, R. C.; Baumgratz, J. F. A; Bicudo, C. E. M.; Canhos, D. A. L.; Carvalho, A. A. Jr.; Coelho, M. A. N.; Costa, A. F.; Costa, D. P.; Hopkins, M. G.; Leitman, P. M.; Lohmann, L. G.; Lughadha, E. N.; Maia, L. C.; Martinelli, G.; Menezes, M.; Morim, M. P.; Peixoto, A. L.; Pirani, J. R.; Prado, J.; Queiroz, L. P.; Souza, S.; Souza, V. C.; Stehmann, J. R.; Sylvestre, L. S.; Walter, B. M. T.; Zappi, D. C. 2012. New Brazilian floristic list highlights conservation challenges. BioScience, 62: 39-45. Doi: https://doi.org/10.1525/bio.2012.62.1.8.

Furtado, R. A.; Rodrigues, E. P.; Araujo, F. R. Oliveira, W. L.; Furtado, M. A.; Castro, M. B.; Cunha, W. R.; Tavares, D. C. 2008. Ursolic acid and oleanolic acid suppress preneoplastic lesions induce by 1, 2-dimethylhydrazine in rat colon. Toxicologic Pathology, 36: 576-580. Doi: https://doi.org/10.1177/0192623308317423.

Gavin, M. C. 2009. Conservation implications of rainforest use patterns: Mature forests provide more resources but secondary forests supply more medicine. Journal of Applied Ecology 46: 1275-1282. Doi: https://doi.org/10.1111/j.1365-2664.2009.01713.x.

Goldenberg, R. 2004. O gênero Miconia (Melastomataceae) no Estado do Paraná, Brasil. Acta Botanica Brasilica, 18: 927-947. Doi: https://doi.org/10.1590/S0102-33062004000400024.

Haridasan, M.; Araújo, G. M. 1988. Aluminium acummulating species in two forest communities in the cerrado region of central Brazil. Forest Ecology and Management, 24: 15-26. Doi: https://doi.org/10.1016/0378-1127(88)90021-7.

IBGE- Instituto Brasileiro de Geografia e Estatística. 2004. Mapa de biomas do Brasil. Rio de Janeiro, IBGE.

Jansen, S.; Watanabe, T.; Smets, E. 2002. Aluminium Accumulation in Leaves of 127 Species in Melastomataceae, with Comments on the Order Myrtales. Annals of Botany 90: 53-64. Doi: https://doi.org/10.1093/aob/mcf142.

Karak, T.; Bhagat, R. M. 2010. Trace elements in tea leaves, made tea and tea infusion: a review. Food Research International, 43: 2234-2252. Doi: https://doi.org/10.1016/j.foodres.2010.08.010.

Leonti, M.; Vibrans, H.; Sticher, O.; Heinrich, M. 2001. Ethnopharmacology of the Popoluca, Mexico: An Evaluation. Journal of pharmacy and pharmacology, 53: 1653-1669. Doi: https://doi.org/10.1211/0022357011778052.

Lisboa, M. S. Pinto, A. S.; Barreto, P. A.; Ramos, Y. J.; Silva, M. Q. O. R.; Caputo, M. C.; Almeida, M. Z. 2017. Estudo etnobotânico em comunidade quilombola Salamina/Putumujú em Maragogipe, Bahia. Revista Fitos, 11: 1-118. Doi: https://doi.org/10.5935/2446-4775.20170006.

Li, L.; Fu, Q. L.; Achal, V.; Liu, Y. 2015. A comparison of the potential health risk of aluminum and heavy metals in tea leaves and tea infusion of commercially available green tea in Jiangxi, China. Environmental monitoring and assessment, 187: 228. Doi: https://doi.org/10.1007/s10661-015-4445-2.

Łuczaj, L. 2010. Plant identification credibility in ethnobotany: a closer look at Polish ethnographic studies. Journal of Ethnobiology and Ethnomedicine, 6: 1-16. Doi: https://doi.org/10.1186/1746-4269-6-36.

Maioli-Azevedo, V.; Fonseca-Kruel, V. S. 2007. Plantas medicinais e ritualísticas vendidas em feiras livres no Município do Rio de Janeiro, RJ, Brasil: estudo de caso nas zonas Norte e Sul. Acta Botanica Brasilica, 21: 263-275. Doi: https://doi.org/10.1590/S0102-33062007000200002.

Martins, A. B.; Semir, J.; Goldenberg, R.; Martins, E. 1996. O Gênero Miconia Ruiz & Pav. (Melastomataceae) no estado de São Paulo. Acta Botanica Brasilica, 10: 267-316. Doi: https://doi.org/10.1590/S0102-33061996000200005.

Meirelles, J. 2015. Filogenia de Miconia seção Miconia subseção Seriatiflorae e revisão taxonômica do clado albicans (Melastomataceae, miconieae). Campinas: Universidade Estadual de Campinas, 217f. Tese de Doutorado. Available from: tinyurl.com/mvdmet3j.

Meirelles, J.; Lima, D. F.; Goldenberg, R. 2016. Miconia astrocalyx (Melastomataceae, Miconieae): a new species from Brazilian Cerrado. Phytotaxa, 257: 187-192. Doi: https://doi.org/10.11646/phytotaxa.257.2.9.

Ministério da Saúde. 2018. Resolução nº 1.417, de 1º de julho de 2018. Diário Oficial da União, Brasília, DF. Available from: tinyurl.com/yckvymdm.

Mitra, S. K.; Kannan, R. 2007. A Note on Unintentional Adulterations in Ayurvedic Herbs. Ethnobotanical Leaflets, 11: 11-15. Available from: https://opensiuc.lib.siu.edu/ebl/vol2007/iss1/3/.

Myers, N.; Mittermeier, R. A.; Mittermeier, C. G.; Fonseca, G. A. B.; Kent, J. 2000. Biodiversity hotspots for conservation priorities. Nature, 403: 853-858. Doi: https://doi.org/10.1038/35002501.

Pasta, P. C.; Durigan, G.; Moraes, I. C. F.; Ribeiro, L. F.; Haminiuk, C. W. I.; Branco, I. G. 2019. Physicochemical properties, antioxidant potential and mineral content of Miconia albicans (Sw.) Triana: a fruit with high aluminium content. Brazilian Journal of Botany, 42: 209-216. Doi: https://doi.org/10.1007/s40415-019-00532-3.

Pieroni, L. G.; Rezende, F. M.; Ximenes, V. F.; Dokkedal, A. L. 2011. Antioxidant activity and phenols from the methanolic extract of Miconia albicans (Sw.) Triana leaves. Molecules, 16: 9439-9450. Doi: https://doi.org/10.3390/molecules16119439.

Posadzki, P.; Watson, L.; Ernst, E. 2013. Contamination and adulteration of herbal medicinal products (HMPs): An overview of systematic reviews. European Journal of Clinical Pharmacology, 69: 295-307. Doi: https://doi.org/10.1007/s00228-012-1353-z.

Rezende, A. R.; Romero, R.; Goldenberg, R. 2014. Sinopse de Miconia seção Miconia DC. (Melastomataceae) no estado de Minas Gerais, Brasil. Bioscience Journal, 30: 273-287. Available from: tinyurl.com/4r6n8mzd.

Rodrigues, J.; Michelin, D. C.; Rinaldo, D.; Zocolo, G. J.; Santos, L. C.; Vilegas, W.; Salgado, H. R. N. 2008. Antimicrobial Activity of Miconia Species (Melastomataceae). Journal of Medicinal Food, 1: 120-126. Doi: https://doi.org/10.1089/jmf.2007.557.

Saporetti Jr., A. W.; Neto, J. A. A. M.; Almado, R. 2003. Fitossociologia de sub-bosque de cerrado em talhão de Eucalyptus grandis W. Hill ex Maiden no município de Bom Despacho-MG. Árvore, 27: 905-910. Doi: https://doi.org/10.1590/S0100-67622003000600017.

Serpeloni, J. M.; Vilegas, W.; Varanda, E. A.; Cólus, I. M. S. 2008. Avaliação in vivo da anticlastogenicidade de extratos de plantas medicinais do gênero Miconia através do teste do micronúcleo. Semina, 29: 47-56. Doi: https://doi.org/10.5433/1679-0367.2008v29n1p47.

Serpeloni, J. M.; Barcelos G. R. M., Mori, M. P.; Yanagui, K.; Vilegas, W.; Varanda, E. A.; Cólus, I. M. S. 2011. Cytotoxic and mutagenic evaluation of extracts from plant species of the Miconia genus and their influence on doxorubicin-induced mutagenicity: an in vitro analysis. Experimental and Toxicologic Pathology, 63: 499-504. Doi: https://doi.org/10.1016/j.etp.2010.03.011.

Silveira, F. A. O.; Oliveira, E. G. 2013. Does plant architectural complexity increase with increasing habitat complexity? A test with a pioneer shrub in the Brazilian Cerrado. Brazilian Journal of Biology, 73: 271-277. Doi: https://doi.org/10.1590/S1519-69842013000200007.

Spessoto, M. A.; Ferreira, D. S.; Crotti, A. E. M.; Silva, M. L. A.; Cunha, W. R. 2003. Evaluation of the analgesic activity of extracts of Miconia rubiginosa (Melastomataceae). Phytomedicine, 10: 606-609. Doi: https://doi.org/10.1078/094471103322331629.

Stepp, J. R.; Moerman, D. E. 2001. The importance of weeds in ethnopharmacology. Journal of ethnopharmacology, 75: 19-23. Doi: https://doi.org/10.1016/S0378-8741(00)00385-8.

Vasconcelos, M. C.; Royo, V. A.; Ferreira, D. S.; Crotti, A. E. M.; Andrade e Silva, M. L.; Carvalho, J. C. T.; Bastos, J. K.; Cunha, W. R. 2006. In vivo analgesic and anti-inflammatory activities of ursolic acid and oleanoic acid from Miconia albicans (Melastomataceae). Zeitschrift für Naturforschung C, 61: 477-482. Doi: https://doi.org/10.1515/znc-2006-7-803.

Voeks, R. A. 2004. Disturbance pharmacopoeias: Medicine and myth from the humid tropics. Annals of the Association of American Geographers, 94: 868-888. Doi: https://doi.org/10.1111/j.1467-8306.2004.00439.x.

WHO- World Health Organization. 2013. WHO traditional medicine strategy: 2014-2023. Geneva, WHO Press. Available from: tinyurl.com/344667wu.

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Published

2022-08-02

How to Cite

Iglesias, D. T., & Fonseca, R. S. (2022). Miconia albicans (Sw.) Triana (canela-de-velho), the new trend plant from the Brazilian Cerrado: contribution to species identification and pharmacological aspects. Agrarian Sciences Journal, 14, 1–9. https://doi.org/10.35699/2447-6218.2022.38438

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